Here's the method Zika causes Guillain-Barre Complication, where the body attacks itself
(picture: Pixabay)A Fresh research sheds light on the method the mosquito-borne Zika causes a uncommon neurological condition, & the findings can have implications for companies working on Zika vaccines, America investigators said on Wednesday. The Zika outbreak that swept out of the Americas in 2015 & 2016 showed the virus can, in uncommon statuses, cause Guillain-Barre, an autoimmune Complication in that the body attacks itself in the aftermath of an contagion. ever ever the Zika attacks nerve cells, scholars weren't sure whether the Guillain-Barre statuses they had seen in Zika patients were caused with an autoimmune response to the Zika contagion or a direct attack with the virus on nerve cells. An autopsy showed inflammation & erosion of the protective sheath known as myelin in 2 nerves, however no directory of the Zika in nerve cells. various companies are emerging Zika vaccines, including Takeda Pharmaceutical Co, that said earlier this 30 days it had begun an early phase security experience.![Here's how Zika virus causes Guillain-Barre disorder, where the body attacks itself](https://s3.ap-southeast-1.amazonaws.com/images.deccanchronicle.com/dc-Cover-gg3omdrio5013oda3crmchibr3-20171214115804.Medi.jpeg)
the method Zika induces congenital microcephaly
As it stated in Zika contagion leads to microcephaly in mice by inducing ER pressure. Coronal sections out of corresponding mouse brains showing the immunolabeling of Zika (NS1, red), deep layer neurons (CTIP2, green), & nuclei (DAPI, blue). Credit: Institut Pasteur Epidemiological researches display which in utero fetal contagion by the Zika (ZIKV) probably lead to microcephaly, an irreversible congenital malformation of the brain characterized by an incomplete Growth of the cerebral cortex. Furthermore, the defects observed are specific to an contagion by ZIKV, as other neurotropical viruses of the flavivirus family (West Nile virus, yellow fever,...) did'nt cause microcephaly, in contrast to Zika. probe more: Zika-linked nerve damage caused by immune response to the virusMore data: Ivan Gladwyn-Ng et al, pressure-induced unfolded protein response contributes to Zika–associated microcephaly, Nature Neuroscience (2017).collected by :Sandra Alex